1Mila Kunis
Dimitrios KambourisYou may have noticed this actress's perfect brows and glowing skin, but her differing eye colors are harder to spot. Kunis suffered from chronic inflammation of the iris for a long time. "I was blind in one eye for many years, and no one knew," she told Cosmopolitan in 2011. Fortunately, as the result of surgery, she is no longer blind in that eye, though the (very pretty) difference in color has lasted.
2Dominic Sherwood
Jon KopaloffThe star of Freeform's Shadowhunters didn't always love his half blue-half brown left eye. In April, he tweeted a message to one child who was bullied for his eye condition: "Your eyes are beyond beautiful," he wrote. "It took me a long time to realise that about mine."
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3Kate Bosworth
Getty ImagesOne of the most well-known instances of heterochromia in Hollywood, Bosworth's eyes are noticeably different in pigmentation, with one being blue and one being a much darker hazel.
4Kiefer Sutherland
Tara ZiembaThough the difference in his eye colors may be subtle, the actor's then-fiancée Julia Roberts alluded to his heterochromia during her Golden Globe acceptance speech in 1990. Though she didn't specifically say his name, Roberts thanked her "beautiful blue-eyed, green-eyed friend."
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5Jane Seymour
Getty Images 6Max Scherzer
Chris Trotman//Getty ImagesThis Washington Nationals pitcher has one of the most extreme cases of heterochromia, with one eye being quite light while the other is very dark.
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7Elizabeth Berkley
Gary GershoffThe Showgirls and Saved by the Bell star is known for more than just great hair and epic one-liners. She also has beautifully unique eyes, with one being half-brown and half-green and the other fully green.
8Josh Henderson
Michael LoccisanoThe handsome actor has two contrasting eye colors. But since they're both in the lighter range, you may not notice immediately that one is a medium blue, and the other a rich green.
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9Bill Pullman
Getty ImagesEveryone's favorite alien-butt-kicking president has the more subtle kind of heterochromia — the sectorial kind — which gives one of his eyes a darker look thanks to a brown area of the iris.
10Alice Eve
Getty ImagesThe She's Out of My League and Star Trek actress's eyes are pretty striking — her left eye is blue, while her right is green. But she told Conan O'Brien during an interview that she actually dated her boyfriend for 9 months before he noticed.
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11Henry Cavill
Getty ImagesThat's right: Superman himself has heterochromia. Is this proof that it's actually a superpower?
12Venus the Cat
What could possibly earn a feline over 2 million Instagram followers? Why, being as unique looking as Venus the two-faced cat! On top of being adorable, her striking coloring has made her an internet sensation.
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13Michael Flatley
Walter McBride//Getty ImagesA brilliant dancer and choreographer, Flatley has one green eye with brown flecks and one blue eye.
14Benedict Cumberbatch
J. Kempin//Getty ImagesCumberbatch’s intriguing eyes are a combination of blue, green, and gold. They may appear blue or green overall depending on the light.
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15Simon Pegg
Michael Loccisano//Getty ImagesPegg’s eyes are mainly blue-grey but the right has a unique brown fleck, giving this funny man and Star Trek alum a striking appearance.
16Olivia Wilde
John Shearer//Getty ImagesThe inner rings of Wilde’s irises are a different color from the outer, lending her blue-green eyes an exotic appearance.
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17Dan Akroyd
Lester Cohen//Getty ImagesWith one green eye and one brown eye, Akroyd has complete heterochromia, which he once discussed with the Daily Mail.
18Christopher Walken
Michael Stewart//Getty ImagesWalken has blue eyes with green inner rings, which are as distinctive as his acting style.
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19Demi Moore
Frazer Harrison//Getty ImagesYou may never have noticed but the lovely Moore has two completely different color eyes: Hazel and green.
20Virginia Madsen
JB Lacroix//Getty ImagesMadsen, an '80s icon and versatile actress often recognized for her role in Sideways, has one green eye and one with brown flecks.
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